Aspartic Acid is a non-essential amino acid, which means that it is manufactured from other amino acids in the liver - it does not have to be obtained directly through the diet.
Aspartic Acid is one of two amino acids (the other is glutamic acid) that has a negatively charged carboxylate group on the side chain. This gives Aspartic Acid an overall negative charge at physiological hydrogen ion concentrations (approximately pH 7.3).
Although Aspartic Acid is considered a non-essential amino acid, it plays a paramount role in metabolism during construction of other amino acids and biochemicals in the citric acid cycle.
It is of paramount importance in the metabolism during construction of other amino acids and biochemicals in the citric acid cycle. Among the biochemicals that are synthesized from aspartic acid are asparagine, arginine, lysine, methionine, threonine, isoleucine, and several nucleotides.
Aspartic acid is needed for stamina, brain and neural health, and assists the liver by removing excess ammonia and other toxins from the bloodstream. It is also very important in the functioning of RNA, DNA, as well as the production of immunoglobulin and antibody synthesis.
Recent studies have shown that Aspartic Acid may increase resistance to fatigue and increase endurance. Deficiency of aspartic acid may cause symptoms such as fatigue and depression.