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Vitamins and minerals

Inositol hexanicotinate

Product code: P09024

Dose

The reference intake for niacin is 16mg/day for adults. 

It was decided that the Tolerable Upper Intake Level of 10 mg nicotinic acid/day defined by the SCF in 2002 would apply. It's been noted that while this is quite a conservative limit, given the slow release of nicotinic acid from inositol hexanicotinate, this should be used given the absence of studies adequately supporting the absence of a flushing effect when dosing inositol hexanicotinate,

A daily dose of 10 mg nicotinic acid given as inositol hexanicotinate would amount to a daily dose of 11 mg inositol hexanicotinate, resulting in release of 2.4 mg inositol upon hydrolysis. 

Gastrointestinal absorption of inositol hexanicotinate varies widely, with an average of 70% of an orally ingested dose absorbed into the bloodstream

Authorised EFSA Health Claims

Niacin contributes to normal psychological function

Niacin contributes to normal energy-yielding metabolism

Niacin contributes to normal functioning of the nervous system

Niacin contributes to the maintenance of normal mucous membranes

Niacin contributes to the maintenance of normal skin

Niacin contributes to the reduction of tiredness and fatigue

 

CR- 14/05/2019

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